Present status of Catharanthus roseus monoterpenoid indole alkaloids engineering in homo- and hetero-logous systems
Catharanthus roseus synthesizes one of the most structurally, chemically and biologically
active phytomolecules monoterpenoids indole alkaloids (MIAs) with having a wide range of
pharmaceutical activities. Being the sole source of antineoplastic MIAs vinblastine and
vincristine C. roseus has become one of the most valued plant. The low in planta availability
of these MIAs and unavailability of alternative chemical synthesis system has enhanced their
demand and equally let to the exorbitant market cost. To bridge this gap alternative …
active phytomolecules monoterpenoids indole alkaloids (MIAs) with having a wide range of
pharmaceutical activities. Being the sole source of antineoplastic MIAs vinblastine and
vincristine C. roseus has become one of the most valued plant. The low in planta availability
of these MIAs and unavailability of alternative chemical synthesis system has enhanced their
demand and equally let to the exorbitant market cost. To bridge this gap alternative …
Present status of Catharanthus roseus monoterpenoid indole alkaloids engineering in homo- and hetero-logous systems.
AS Abhishek Sharma, DA Dhruti Amin… - 2020 - cabidigitallibrary.org
Catharanthus roseus synthesizes one of the most structurally, chemically and biologically
active phytomolecules monoterpenoids indole alkaloids (MIAs) with having a wide range of
pharmaceutical activities. Being the sole source of antineoplastic MIAs vinblastine and
vincristine C. roseus has become one of the most valued plant. The low in planta availability
of these MIAs and unavailability of alternative chemical synthesis system has enhanced their
demand and equally let to the exorbitant market cost. To bridge this gap alternative …
active phytomolecules monoterpenoids indole alkaloids (MIAs) with having a wide range of
pharmaceutical activities. Being the sole source of antineoplastic MIAs vinblastine and
vincristine C. roseus has become one of the most valued plant. The low in planta availability
of these MIAs and unavailability of alternative chemical synthesis system has enhanced their
demand and equally let to the exorbitant market cost. To bridge this gap alternative …
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